Functional medicine is an individualized and tailored approach that addresses the underlying causes of disease using a systems-oriented approach to engage both patient and practitioner through a therapeutic partnership. It uses lifestyle interventions and dietary supplementation to address the causes of a person's symptoms. Functional Medicine shift away from the traditional disease-centered focus of medical practice to a more patient-centered approach that address the root causes rather than merely treating symptoms. 

Through Functional Medicine, Dr. Wang treats patients individually, spends time with them, and stimulates behavioral changes that lead to better health outcomes. Dr Wang considers root causes, as opposed to simply treating the symptoms. Functional Medicine creates health.

Commonly ordered laboratory values are : Hemoglobin A1c, C-Reactive Protein, Homocysteine, Lymphocyte Response Assay, Urine pH, Vitamin D, Omega 3:6 EFA Ratio, and 8-Oxo-Guanine.

  1. Maskell, James. The Evolution of Medicine: Join the Movement to Solve Chronic Disease and Fall Back in Love with Medicine (p. 31). Knew Publishing. Kindle Edition. 

Ketogenic Diet

Neuroketotherapeutics is a type of medal therapy that uses bioenergetics through various dietary and exercise methods to induce ketosis. These therapies include medium-chain triglyceride supplements, ketone esters supplementation, fasting, strenuous exercise, modified Atkins diet, and classic ketogenic diet.

Historically, the Ketogenic Diet was first used to control epilepsy in children. How the ketogenic diet works is still being investigated. Research indicates that it  may change the way cells function (enhance mitochondrial respiration, promote neuronal long-term potentiation, increase BDNF expression, increase GPR signaling, attenuate oxidative stress, reduce inflammation, and alter protein post-translational modifications via lysine acetylation and β-hydroxybutyrylation) and the way the body responds downstream from the cell signals (Akt, PLCγ, CREB, Sirtuin, and mTORC pathways). (1)

 A 2017 review summarized available scientific research investigating the ketogenic diet's affect on cancer. The majority (72%) of the 29 available animal studies showed evidence of an anti-tumor effect. The 24 human studies showed possible anti-tumor effects in some individual cases without any evidence of pro-tumor effects.(2)

Complications include protein-losing enteropathy,(3) possible osteoporosis,(4,5) possible changes in lipid profiles (5). A strict ketogenic diet should be initiated under physician supervision and routine monitoring.  

  1. Koppel SJ, Swerdlow RH. Neuroketotherapeutics: A modern review of a century-old therapy. Neurochem Int. 2017 Jun 1. pii: S0197-0186(17)30227-9. doi: 10.1016/j.neuint.2017.05.019. [Epub ahead of print] Review.
  2. Klement RJ. Beneficial effects of ketogenic diets for cancer patients: a realist review with focus on evidence and confirmation. Med Oncol. 2017 Aug;34(8):132. doi: 10.1007/s12032-017-0991-5. Epub 2017 Jun 26. Review.
  3. Ahn WK, Park S, Kim HD. Protein-Losing Enteropathy as a Complication of the Ketogenic Diet. Yonsei Med J. 2017 Jul;58(4):891-893. doi: 10.3349/ymj.2017.58.4.891.
  4. Wu X, Huang Z, Wang X, Fu Z, Liu J, Huang Z, Kong G, Xu X, Ding J, Zhu Q. Ketogenic Diet Compromises Both Cancellous and Cortical Bone Mass in Mice. Calcif Tissue Int. 2017 May 25. doi: 10.1007/s00223-017-0292-1.
  5. Colica C, Merra G, Gasbarrini A, De Lorenzo A, Cioccoloni G, Gualtieri P, Perrone MA, Bernardini S, Bernardo V, Di Renzo L, Marchetti M. Efficacy and safety of very-low-calorie ketogenic diet: a double blind randomized crossover study. Eur Rev Med Pharmacol Sci. 2017 May;21(9):2274-2289.
 
 

 
 
 

 
“Dr. Wang is well versed in intermittent fasting and ketogenic diets.”
 

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